• Beckman WF, Lermo Jimenez MA, Moerland PD, Westerhoff HV and Verschure PJ: 4sUDRB-sequencing for genome-wide transcription bursting quantification in breast cancer cells. Preprint BioRxiv:
  • Borgoni S, Sofyali E, Soleimani M, Wilhelm H, Muller-Decker K, Will R, Noronha A, Beumers L, Verschure, PJ Yosef Yarden, Magnani L, van Kampen AHC, Moerland PD, Wiemann S. Time-resolved profiling reveals ATF3 as a novel mediator of endocrine resistance in breast cancer. Cancers 12 (10) 2918.
  • Gjaltema RAF, Goubert G, Huisman C, Consuelo del PGT, Koncz M, Jellema PG, Wu D, Brouwer U, Kiss A, Bank RA, Verschure PJ, Rots MG. KRAB-induced heterochromatin is sufficient to achieve mitotocally stable PLOD2 gene repression in somatic cells. Int J. Mol. Sci. 21: 3634-3657.
  • Soleimani M, Borgoni S, Sofyali E, Verschure PJ, Wiemann S, Moerland P, Kampen AHC. Candidate methylation sites associated with endocrine therapy resistance in ER+/HER2- breast cancer. BMC Cancer, 20: 676.
  • Mandemaker IK, Zhou D, Bruens ST, Dekkers DH, Verschure PJ, Edupuganti RR, Meshorer E, Demmers JA, Marteijn JA. H1 eviction by the histone chaperone SET reduces cell survival following DNA damage. J. Cell Sci. 133, JCS 235473.



  • Naue J, Sänger T, Hoefsloot HCJ, Lutz-Bonengel S, Kloosterman AD, Verschure PJ (*corresponding author) (2018): Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing. Forensic Sci Int Genet. 7;36:152-159.
  • Beckman W, Vuist IM, Kempe H, *Verschure PJ (*corresponding author). (2018) : Cell-to-cell transcription variability as measured by single molecule RNA FISH to detect epigenetic state switching. Methods Mol Biol 1767: 385-393.
  • Naue J, Hoefsloot HCJ, Kloosterman AD, Verschure PJ. Forensic DNA methylation profiling from minimal traces: How low can we go? (2018) Forensic Sci Int Genet. 33:17-23.


  • Naue J, Hoefsloot HCJ, Mook ORF, Rijlaarsdam-Hoekstra L, van der Zwalm MCH, Henneman P, Kloosterman AD, *Verschure  PJ (*corresponding author). (2017): Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression, FSI: Genetics  31: 19-28.
  • Goubert D, Beckman WF, Verschure PJ, Rots MG (2017): Epigenetic Editing: towards realization of the curable genome concept. Converg. Sci. Phys. Oncol 3:6.
  • van Hagen M, Piebes DGE, de Leeuw WC, van Roon-Mom WMC, Moerland PD, *Verschure PJ (*corresponding author). (2017): ­­­The dynamics of early-state transcriptional changes and aggregate formation in a Huntington’s disease cell model. BMC Genomics 28: 73.
  • Magnani L, Frigè G, Gadaleta RM, Corleone G, Fabris S, Kempe H, Verschure PJ, Barozzi I, Vircillo V, Hong SP, Perone Y, Saini M, Trumpp A, Viale G, Neri A, Ali S, Colleoni MA, Pruneri G, Minucci S. (2017): Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer Nat Genet 49:444.


  • Hoeijmakers, L., Kempe, H., & Verschure, P. J. (2016). Epigenetic imprinting during assisted reproductive technologies: The effect of temporal and cumulative fluctuations in methionine cycling on the DNA methylation state. Molecular Reproduction and Development, 83(2), 94-107. DOI: 10.1002/mrd.22605 [details]
  • Wijchers, P. J., Krijger, P. H. L., Geeven, G., Zhu, Y., Denker, A., Verstegen, M. J. A. M., ... de Laat, W. (2016). Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments. Molecular Cell, 61(3), 461-473. DOI: 10.1016/j.molcel.2016.01.001 [details / files]


  • Kempe, H., Schwabe, A., Crémazy, F., Verschure, P. J., & Bruggeman, F. J. (2015). The volumes and transcript counts of single cells reveal concentration homeostasis and capture biological noise. Molecular Biology of the Cell, 26(4), 797-804. DOI: 10.1091/mbc.E14-08-1296 [details / files]


  • Anink-Groenen, L. C. M., Maarleveld, T. R., Verschure, P. J., & Bruggeman, F. J. (2014). Mechanistic stochastic model of histone modification pattern formation. Epigenetics & Chromatin, 7, 30. DOI: 10.1186/1756-8935-7-30 [details / files]


  • Brink, M. C., Piebes, D. G. E., de Groote, M. L., Luijsterburg, M. S., Casas-Delucchi, C. S., van Driel, R., ... Verschure, P. J. (2013). A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement. PLoS One, 8(7), e69347. DOI: 10.1371/journal.pone.0069347 [details] [PDF]
  • Muraro, M. J., Kempe, H., & Verschure, P. J. (2013). Concise Review: The Dynamics of Induced Pluripotency and Its Behavior Captured in Gene Network Motifs. Stem Cells, 31(5), 838-848. DOI: 10.1002/stem.1340 [details] [PDF]


  • de Groote, M. L., Verschure, P. J., & Rots, M. G. (2012). Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes. Nucleic Acids Research, 40(21), 10596-10613. DOI: 10.1093/nar/gks863 [details] [PDF]


  • Schwabe, A., Dobrzynski, M., Rybakova, E., Verschure, P. J., & Bruggeman, F. J. (2011). Origins of stochastic intracellular processes and consequences for cell-to-cell variability and cellular survival strategies. Methods in Enzymology, 500, 597-625. DOI: 10.1016/B978-0-12-385118-5.00028-1 [details]


  • Scassellati, C., Albi, E., Cmarko, D., Tiberi, C., Cmarkova, J., Bouchet‑Marquis, C., ... Fakan, S. (2010). Intranuclear sphingomyelin is associated with transcriptionally active chromatin and plays a role in nuclear integrity. Biology of the Cell, 102(6), 361-375. DOI: 10.1042/BC20090139 [details]


  • Luijsterburg, M. S., Dinant, C., Lans, H., Stap, J., Wiernasz, E. S., Lagerwerf, S., ... van Driel, R. (2009). Heterochromatin protein 1 is recruited to various types of DNA damage. Journal of Cell Biology, 185(4), 577-586. DOI: 10.1083/jcb.200810035 [details] [PDF]
  • Mateos-Langerak, J., Bohn, M., de Leeuw, W., Giromus, O., Manders, E. M. M., Verschure, P. J., ... Goetze, S. (2009). Spatially confined folding of chromatin in the interphase nucleus. Proceedings of the National Academy of Sciences of the United States of America, 106(10), 3812-3817. DOI: 10.1073/pnas.0809501106 [details]


  • Verschure, P. J. (2008). Finger pointing: engineered zinc finger proteins allow precise modification and regulation of genes. Chemistry & Biology, 15, 1241-1242. DOI: 10.1016/j.chembiol.2008.12.001 [details]